The accessibility of spaces, facilities and services is one of the essential requirements of contemporary models that, in the ethics of a proper inclusive design, undertake important strategies for the realization of socially sustainable architectures with a consequent achievement of greater environmental quality and enhancement of public goods. In this context some Institutes of Friuli Venezia Giulia are working (ref. Regional Council of Associations of Persons with Disabilities and their Families of FVG). They, in collaboration with some Courses of Architecture of the University of Udine and Trieste, have start lines of applied research aimed to promoting the culture of inclusion. Here, is particular the participatory process developed in the design of multisensory accessibility; this essay describes the research context for proposing an interpretation of the potentialities and strengths that a careful design on sense-perceptual deficits can makes to the design of Social Housing spaces.